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What is inolimomab (LEUKOTAC®)

What is inolimomab (LEUKOTAC®)?

Inolimomab (LEUKOTAC®) is an immunotherapy monoclonal antibody that targets the interleukin-2 receptor (IL-2), a chemical molecule named cytokine that contributes to the development and proliferation of some white blood cells including T-cells responsible for aGvHD. By linking specifically to the α chain of the receptor (CD25), inolimomab (LEUKOTAC®) prevents IL-2 from binding on the surface of the donor’s over-active T-cells which blocks their multiplication.

The efficacy of inolimomab (LEUKOTAC®) in steroid-resistant aGvHD lies mainly in its specificity and its preferential affinity to the CD25 receptor found on the surface of T-lymphocytes.

Mode of action of inolimomab (LEUKOTAC®)

Latest news on inolimomab (LEUKOTAC®)

Discover our latest news regarding our pipeline, our partnerships and more

Mon, 02/18/2019 - 08:46 - Tue, 02/01/2022 - 09:00

Elsalys Biotech SAS, a 2013 spinout from Transgene SA, achieved a significant milestone with the finding that lead candidate inolimomab (Leukotac)

Thu, 04/05/2018 - 09:00
  • ELSALYS BIOTECH plans to submit to the European Medicines Agency before summer 2018 a Paediatric Investigation Plan (PIP) proposing to c

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